„Je potřeba podpořit všechny stakeholdery, aby se zlepšili datovou infrastrukturu a využití údajů včetně zapojení moderních nástrojů typu umělé inteligence a vysoce výkonné výpočetní techniky. Tradiční onkologické registry, které již dlouhou dobu představují páteř onkologických dat, by měly být důležitou, ale ne jedinou součástí moderního onkologického informačního systému. Poskytovatelé onkologické péče potřebují snadno sdílet data, aby mohli v komplexních onkologických centrech poskytovat péči skutečně za
Archív kategorií: Krátke postrehy
Cureus | Physician Suicide in the Era of the COVID-19 Pandemic
Over the last several decades, physician burnout has become more prevalent because of increasing workloads, increasing administrative burden, and time spent on electronic medical records, among several other reasons [11]. The rate of suicidal ideation among physicians is almost twice as high as the general population at 7.2% vs. 4%. In addition, studies on mortality related to suicide show that the rates of suicides in physicians are consistently higher than in the general population
Zdroj: Cureus | Physician Suicide in the Era of the COVID-19 Pandemic
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients | NEJM
After oral administration of molnupiravir, NHC circulates systemically and is phosphorylated intracellularly to NHC triphosphate. NHC triphosphate is incorporated into viral RNA by viral RNA polymerase and subsequently misdirects the viral polymerase to incorporate either guanosine or adenosine during viral replication. This leads to an accumulation of deleterious errors throughout the viral genome that ultimately render the virus noninfectious and unable to replicate.
Zdroj: Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients | NEJM